研究方向及主要成就：
多年來一直致力于有機(jī)合成、有機(jī)合成方法學(xué)、藥用高分子材料等領(lǐng)域的研究工作，近年來在不對稱有機(jī)合成、核糖核酸和脫氧核糖核酸的合成、金屬有機(jī)化學(xué)、配位化學(xué)、晶體學(xué)、生物學(xué)等領(lǐng)域也有重要的研究成果，曾在《Nature》、《J. Am. Chem. Soc.》、《Chemistry & Biology》、《Molecular Microbiology》、《Chem. Eur. J.》、《Organic Letters》、《Organometallics》等上發(fā)表論文近百篇，引用次數(shù)超過1000次。并申請美國、歐洲專利六十項。
作為主要參加者在《Nature》雜志、作為共同第一作者在《Chemistry & Biology》雜志上發(fā)表了關(guān)于新型氨基酸吡咯賴氨酸的全合成與生物活性研究的文章，這兩篇文章被國際著名雜志和媒體廣泛報道。被譽(yù)為解決了近半個多世紀(jì)以來遺傳基因編碼中的一個難題并擴(kuò)展了遺傳基因編碼的規(guī)則。作為項目技術(shù)負(fù)責(zé)人承擔(dān)了加州大學(xué)重大科研項目和抗腫瘤藥物重大國際合作項目。2011年到四川大學(xué)從事制藥工程領(lǐng)域的研究與開發(fā)工作。主要從事抗腫瘤藥物的設(shè)計、合成、不對稱催化、手性識別、納米運(yùn)載體系和生物活性等領(lǐng)域的研究。
代表性文章：
1. Shiqi Zhang, Guangxun Li, Ling Li, Xiongfei Deng, Gang Zhao,* Xin Cui, and Zhuo Tang*, Alloxan-Catalyzed Biomimetic Oxidations with Hydrogen Peroxide or Molecular Oxygen, ACS Catalysis, 2020, 10, 245?252
2. Xiongfei Deng, Yingwei Wang, Shiqi Zhang, Ling Li, Guangxun Li,* Gang Zhao* and Zhuo Tang, An organocatalytic asymmetric Friedel–Crafts reaction of 2-substituted indoles with aldehydes: enantioselective synthesis of a-hydroxyl ketones by low loading of chiral phosphoric acid, Chem. Comm., 2020, 56, 2499--2502
3. Haihang Zhao，Yuan Cao， Yanjing Zhang， Yangyang Zhou， Gang Zhao*， Lin Pu*， Spectroscopic studies of a BINAM-based sensor: Highly selective fluorescent recognition of lysine in water solution through a nucleophilic substitution reaction, Tetrahedron Letters， 2019，60，1238-1242
4. Haihang Zhao，Yuan Cao，Yanjing Zhang，Yangyang Zhou，Gang Zhao*， Lin Pu*， Study of the Zn-II Complexes of 1,1-Binaphthyl-Based Schiff Bases: Fluorescent Detection of Thiocyanate, Eur. J. Inorg. Chem.， 2018, 37, 4153-4157
5. Guidong Gong, Yuan Cao, Hongyun Qian, Yangyang Zhou, Haihang Zhao, Ling Li, Fei Wang* and Gang Zhao*, Assessment of the antitumor activity of a cyclopalladated ferrocene compound assisted by a dual-targeting drug delivery system, Chem. Commun., 2018, 54(60), 8312 -8315
6. Guidong Gong, Yuan Cao, Fei Wang*, and Gang Zhao* Planar Chiral Ferrocene Cyclopalladated Derivatives Induce Caspase-Dependent Apoptosis and Antimetastasis in Cancer Cells, Organometallics, 2018, 37(7), 1103–1113
7. Yanjin Zhang, Gang Zhao*, Lin Pu*，Diastereoselective [4+1] Cycloaddition of Alkenyl Propargylic Tertiary Acetates with CO Catalyzed by [RhCl(CO)2]2，Eur. J. Org. Chem.，2017，47，7026-7033
8. Yingwei Wang, Guangxun Li, Hongxin Liu, Zhuo Tang*, Yuan Cao and Gang Zhao*，A tandem annulation with a [1,3]-hydride transfer as the key step leading to isochromans，Chem. Commun., 2017, 53, 10652—10655
9. Ting Song, Yuan Cao, Gang Zhao*, and Lin Pu*, Fluorescent Recognition of Zn2+ by Two Diastereomeric Salicylaldimines: Dramatically Different Responses and Spectroscopic Investigation，Inorg. Chem.，2017, 56, 4395?4399
10. Shiqi Zhang, Guangxun Li, Hongxin Liu, Yingwei Wang, Yuan Cao, Gang Zhao* and Zhuo Tang*，Bio-inspired enantioselective full transamination using readily available cyclodextrin，RSC Advances, 2017, 7, 4203–4208
